DDMODEL00000322: HCQ popPK model

Short description:
Population pharmacokinetics of Hydroxychloroquine in COVID-19 patients :- final 1-compartment model with with first order absorption- description of blood concentrations- 400 BID on day 1, followed by 200 mg the subsequent days for a 5 days.
Original code |
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Pauline THEMANS
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Context of model development: | Mechanistic Understanding; |
Model compliance with original publication: | Yes; |
Model implementation requiring submitter’s additional knowledge: | No; |
Modelling context description: | Population pharmacokinetic modeling of hydroxychloroquine in COVID-19 patients; |
Modelling task in scope: | estimation; |
Nature of research: | Clinical research & Therapeutic use; |
Therapeutic/disease area: | Anti-infectives; |
Annotations are correct. |
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This model is not certified. |
- Model owner: Pauline THEMANS
- Submitted: May 9, 2020 10:35:39 AM
- Last Modified: Aug 20, 2020 9:18:01 AM
Revisions
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Version: 18
- Submitted on: Aug 20, 2020 9:18:01 AM
- Submitted by: Pauline THEMANS
- With comment: Edited model metadata online.
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Version: 12
- Submitted on: May 11, 2020 11:52:51 AM
- Submitted by: Pauline THEMANS
- With comment: Edited model metadata online.
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Version: 10
- Submitted on: May 10, 2020 8:34:13 AM
- Submitted by: Pauline THEMANS
- With comment: Edited model metadata online.
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Version: 7
- Submitted on: May 9, 2020 10:35:39 AM
- Submitted by: Pauline THEMANS
- With comment: Edited model metadata online.